In 2005, doctors in the Department of Psychiatry at the University of Rennes began using Transcranial Magnetic Stimulation (TMS) as a treatment for depression. Very quickly, they expressed the need for a reliable and precise means of localisation. A very simple to use equipment in order to make the TMS Magnetic Stimulation reproducible.

A collaboration then began with the VISAGES research team at INRIA / INSERM, already active in image-guided neurosurgery, to develop this innovative tool.

This collaboration resulted in a unique neuronavigator for TMS, derived from neurosurgery tools. This neuronavigator is specifically designed to guide TMS in routine therapeutic use. Named SYNEIKA ONE, it allows an accelerated learning curve and preserves a high productivity.


Winner of the i-LAB competition in 2008 and 2011, supported by BPI France and the Brittany Region, SYNEIKA was created in 2009. The process of automatic localisation of anatomical targets on individual MRI is patented the same year.



Syneika's Quality Management System is ISO 13485 certified and the Syneika One neuronavigator is CE marked as a class IIb medical device and marketed.



The Centre Hospitalier le Vinatier (69) and the CESAME (49) trust Syneika.



Syneika has partnered with Mag&More to offer a global solution for neuronavigated Transcranial Magnetic Stimulation, enabling precision medical treatment that respects the operator and the patient.



A first PowerMAG transcranial magnetic stimulator is delivered to the Lille University Hospital.

Beginning of a collaboration with Axilum Robotics: a TMS-Robot is piloted for the first time by a Syneika One neuronavigator in version 2 at the Ambroise Paré Hospital for clinical research on neuropathic pain, within the INSERM U987 Unit.



Following the Ambroise Paré Hospital, Syneika equips its first clients for the treatment of chronic pain by Transcranial Magnetic Stimulation (TMS).

Remote maintenance of the equipment is implemented through a secure connection certified by the ANSSI.



First international success in Indonesia for a Syneika One neuronavigator, in combination with a TMS-Robot from Axilum-Robotics.

Syneika equips the Department of Adult Psychiatry of the University Hospitals Pitié Salpêtrière.



The new version 2.1 of Syneika One brings the connection to PACS and better guidance accuracy.



Syneika One neuronavigators, in combination with Axilum-Robotics TMS-Robots, are in use in Bruges, Belgium, and on Reunion Island at the Les Flamboyants Clinic.



Syneika and the MediCIS research team (INSERM/LTSI/University of Rennes 1) are collaborating to optimise the automatic identification of anatomical targets on individual MRI scans.



Syneika One now offers automatic identification of somatotopic representations of the face and lower limb of the primary motor cortex, to help caregivers better individualise the treatment of chronic pain.



An 8th Syneika One neuronavigator is put into service in Indonesia.

Since it was first marketed, the Syneika One neuronavigator has enabled the precise treatment of 10,000 patients, during 150,000 sessions of neuronavigated Transcranial Magnetic Stimulation.